Priligy for Premature Ejaculation

Premature ejaculation (PE) is the most common form of sexual dysfunction to affect men of all ages. In Australia, it affects up to 31% of men, though the actual number could be much higher due to the discomfort that comes from speaking about it with doctors. It is when a man ejaculates always or nearly always prior to or within about 1 to 3 minutes of sexual activity. 

It can be an embarrassing topic to talk about, so men with PE often do not seek treatment. However, there are various premature ejaculation medications that can be prescribed to help. Priligy is a premature ejaculation treatment that is only available via prescription in Australia, so it’s important to understand how it works in order to safely use it to treat PE.

What is Priligy?

Priligy is a brand name medication that is prescribed for treating premature ejaculation. The active ingredient in Priligy is Dapoxetine. Dapoxetine and Priligy are selective serotonin reuptake inhibitors (SSRIs), a class of drugs that are typically prescribed as antidepressants. However, unlike other SSRIs, Dapoxetine is absorbed and eliminated rapidly in the body, making it an effective treatment for PE when taken as needed. Priligy comes in 30mg tablets that are taken orally.

How does Priligy work for premature ejaculation?

Selective serotonin reuptake inhibitors (SSRIs) work by increasing serotonin levels in the brain. Serotonin (5-HT receptors) is the chemical that influences mood, emotions and sleep. SSRIs block 5-HT reuptake and can lead to delayed ejaculation, which is why they are prescribed at a lower dose than when used as antidepressants to help treat PE. 

Priligy and Dapoxetine are short-acting SSRIs that were specifically designed to provide on-demand treatment for premature ejaculation. It is recommended to take Priligy 1 to 3 hours before sex. Studies have found that men who took Priligy were able to increase time to ejaculation by an average of up to 3.6 minutes compared to 1.9 minutes for the placebo, indicating that Priligy is an effective treatment for PE.

Side effects of Priligy

Like all medications, there are potential side effects when taking Priligy. The most common mild side effects include:
- Nausea
- Headaches
- Dizziness

More serious side effects can occur. If you experience any of the following, call 000 for assistance.
- Fainting
- Seizures
- Blurred vision

Priligy compared to other premature ejaculation treatments

How does Priligy compare to other PE treatments? Because it is the only SSRI that is designed to be used for on-demand premature ejaculation treatment, it is often preferred by patients over other medications that need to be taken daily, such as Fluoxetine or Paroxetine. Clinical studies have shown its efficacy in improving ejaculation time when taken 1 to 3 hours before sex. 

Other SSRIs that are commonly prescribed off-label for PE include Fluoxetine (Prozac) and Paroxetine. When used for PE, both of these SSRIs are prescribed at a lower dose than when used for depression and mood disorders. They are both long-acting SSRIs and need to be taken daily in order to be effective. 

Is Priligy safe?

Yes, Priligy is safe to use to treat premature ejaculation. However, it may not be suitable for men with a history of depression or other mental health disorders, low blood pressure or other heart problems, liver problems or kidney problems. Priligy should not be taken together with any medications to manage your mood such as antidepressants. It is important to disclose as much accurate medical information as possible to your doctor to assist them in providing the most appropriate treatment options for you.

Depending on your medical history, symptoms and needs, your doctor will prescribe an appropriate premature ejaculation treatment. Like all medications, there are potential side effects to be aware of. Always use your prescription medication exactly as prescribed and contact your doctor if you’re experiencing any issues.

Now you can get genuine, clinically proven PE medication online through Rosemary. Online assessments are 100% confidential and take about 5 minutes to complete. Start your visit with an online doctor for premature ejaculation treatment today.


Translational Andrology and Urology (December 2013) - Dapoxetine and the treatment of premature ejaculation
Scientific Reports (December 2014) - The role of dapoxetine hydrochloride on-demand for the treatment of men with premature ejaculation
Medical Science Monitor (June 2019) - Efficacy and Safety of “On-Demand” Dapoxetine in Treatment of Patients with Premature Ejaculation: A Meta-Analysis
Annals of Saudi Medicine (October 2018) - Dapoxetine for the treatment of premature ejaculation: a meta-analysis of randomized controlled trials with trial sequential analysis
Australian Family Physician (October 2015) - Premature ejaculation: A clinical review for the general physician

ARTG Registered Medications:

Product PRILIGY dapoxetine 30 mg (as hydrochloride) film-coated tablet blister pack is registered in the ARTG, AUST R

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